Even so, there's always the worry that some infection might sneak through, and that was enough to get DeChambeau's formidable mind wondering.
It was the second straight year there was a five-way share of the lead through 36 holes.
Johnson, the PGA Player of the Year after winning the Tour Championship, has been runner-up in three of the past six majors and will focus on the par-5 holes, hoping his long-driving game helps make the difference.
Meanwhile, reigning champion Tiger Woods also impressed on his return to Augusta, shooting four under par after a blistering start to his Masters campaign.
Where Friday night's leaders will stand heading into the final 36 holes won't be determined until the rest of the field finishes the second round on Saturday morning. The last group was finishing up its 15th hole. It caused a delay of almost three hours at the start of the tournament that caused the opening two rounds to need an extra day to finish, and it made Augusta National as vulnerable as ever.
It was the 20th anniversary of his 2000 victory at Augusta National.
Turns out, the green jacket will not be draped over the biggest, strongest shoulders - not if they belong to a guy who has no idea where that little white ball is going.
"It's definitely not as low as I feel like I could or should be, but we're in good position going into the weekend", he said.
However, with the top 50 and ties making the cut, it is academic that he will advance.
"The golf course is playing long right now".
The tournament began on Thursday with record low scoring, and for a while, you could even be excused for wondering if this was really the Masters.
DeChambeau was right on the borderline for the cut. "I know the subtle nuances".
SportsCenter at the Masters will air on ESPN Saturday morning from 7 a.m. until play resumes at 7:30 a.m.
The likes of Jon Rahm, Paul Casey, Bryson DeChambeau and Tiger Woods are now on the back nine completing their second rounds before the halfway cut will see the top 50 and ties through to the final 36 holes.
World No. 1 Dustin Johnson is among four players to have grabbed a share of the lead at nine under par before play was suspended.
It would, however, lead to a triple-bogey seven and drop the American well out of contention.
Bryson DeChambeau, a heavy favourite before the event, shot 70 in his first round, but was 3-over for 12 holes in the second.
"There have been so many great players here before me, including the ones we just talked about, from Jack Nicklaus to Gary Player to all the greats that have competed here, and to be the oldest to make the cut, it's certainly an achievement".
Germany's 63-year-old Bernhard Langer became the oldest player to make the cut in Masters history on 141.