Tither-Kaplan toldThe Times, Franco removed protective plastic guards while filming a nude orgy scene with her and other actresses, the plastic guards were covering other actresses' vaginas faking oral sex on them.
During a film shoot at a strip club, Franco allegedly became angry when the women involved in the scene wouldn't take their tops off.
A fifth woman, Violet Paley, who had previously spoke out against him on Twitter, said that she met Franco in early 2016 and began a consensual sexual relationship with him that turned into him pressuring her to perform oral sex on him while sitting in a vehicle.
Tither-Kaplan and Paley both say Franco apologized to them past year in the wake of the Harvey Weinstein scandal that kicked off of the #MeToo movement, but both say they found his apology insufficient.
"Look, in my life I pride myself on taking responsibility for things that I have done", he told Colbert.
The Deuce actor told Meyers, "There are people that need to be heard. It's a good thing and I support it".
"The things I heard are not accurate, but I completely support people coming out because they didn't have a voice for so long", he explained.
"I want to give him credit for at least being open to communicating with me", she said. To get out of the situation, she says she told Franco she could see someone near the auto. The alleged misconduct occurred at Studio 4 in Los Angeles and NY, the film school Franco launched where he taught and mentored those wanting to become actors and filmmakers.
Actress Ally Sheedy was among those to question his victory, in tweets that have since been deleted. Aspiring filmmaker Violet Paley also alleged an incident in which Franco, who she was in a romantic relationship with at the time, pressured her into performing oral sex in a vehicle.
Like he noted on The Late Show, Franco reiterated that the allegations made "were not accurate". I don't know. I can't speak for her.
Former students spoke of an alleged unprofessional culture at Franco's now-closed acting school Studio 4, where he taught a sex scenes class. "Our instructors were excellent, student feedback was positive".
Another student, Hilary Dusome claimed Franco would act inappropriately on film sets, creating a hostile environment.
James also said that he didn't want to respond to the claims because he wants the conversation about sexual harassment in Hollywood to continue.
A request for comment from Franco's attorney, Michael Plonsker, was not immediately returned to ABC News.
"If I have to take a knock because I am not going to try and actively refute things then I will, because I believe in it that much".