"We need to assess him and I'm not too optimistic about him playing".
The 25-year-old suffered what the north London club has described as significant ankle ligament damage in a challenge with Manchester City'sFabian Delph in their Champions League quarter-final clash at Tottenham's new stadium on Tuesday.
"Today there are a lot of techniques to try to help that and not become chronic and, of course, because we have very good people here", he said. I'm not optimistic about tomorrow, I am more optimistic he will be available for Man City in the second leg.
A leading surgeon has said that Kane might have to consider surgery in order to prevent him from being susceptible to this type of injury in the future.
And now, as quoted by BBC Sport, Pochettino has admitted he finds it unlikely that Spurs fans will see their captain in action again this season.
Pochettino added that he would rotate his squad against Huddersfield due to injury and fatigue but stressed the importance of picking up three points as Spurs battle to finish in the top four and secure a Champions League spot.
The return game is scheduled for April 17 in Manchester. I was speaking to him before and we need to assess every day to properly answer to see when he can come back to train with the team.
"It looks like a similar [injury he suffered against United], but next week we'll have a proper answer because he needs to see the specialist and see his rehab".
Erik Lamela and Serge Aurier (both hamstring) remain sidelined.