Anderson played Judge Harold "Harry" T. Stone on "Night Court" from 1984 to 1992.
Anderson's comedic acting took him from the street corners to college campuses and small clubs before landing on SNL eight times and Late Night with David Letterman.
Asheville Police Department PIO Christina Hallingse told WSPA they were called to a home early Monday morning where Anderson died.
Anderson would go on after Night Court to star as Dave Barry in CBS' Dave's World from 1993 to 1997.
There were no publicly known health issues for Harry Anderson, though he had lived a quieter life since Night Court's run ended, continuing to perform on a daily basis but a bit further from the spotlight.
He later appeared as the original Richie character in the made-for-TV adaptation of Stephen King's "It," which was recently remade into a movie. Guest appearance on comedy shows like Comedy Bang!
The performer passed away aged 65, according to IMDB.
The magician-turned-actor first made a name for himself on Season 1 of Cheers.
Anderson, also an illusionist and comic, moved from Hollywood to New Orleans in 2000, opening a magic shop and nightclub in the French Quarter, where he also lived.
Anderson, was born in Newport, Rhode Island, on October 14, 1952. Our thoughts are with Anderson's family and friends during this time of mourning.
For all his TV success, Anderson always remained a magician and illusionist at heart. This is a tremendously sad end for an actor who has been known very much over the years for his ability to make viewers laugh.
He's survived by 2 children and his wife, Elizabeth Morgan.