Victoria Jones/PA Images via Getty Images A sign for a Kate Spade shop in Covent Garden, London.
Spade is survived by her daughter and husband, brother of actor David Spade.
He also shares that Kate was actively seeking help for her depression and anxiety for the last five years, and was proactive about seeing a doctor on a regular basis and taking medication to treat her symptoms.
She walked away from the company in 2007, a year after it was acquired from the Neiman Marcus Group for $125 million (then known as Liz Claiborne Inc.).
"But we certainly miss our bright, sunshiney little person", he tells the newspaper, adding that his daughter would have been gratified to know the discourse surrounding her death had potential to help someone else.
Kate Spade'shandbags feature vibrant colors and eye-catching polka dots, just as smile-inducing as the quirky quotes - "bright like glitter, and bubbly like Champagne" - that adorn the walls of the fashion designer's stores.
Frances Valentine, with which she was involved until her death, focuses exclusively on shoes and handbags. And she changed her name to Katherine Noel Frances Valentine Brosnahan Spade. Over a decade ago, she sold the business and later launched a luxury line Frances Valentine.
Spade was born in Kansas City, MO, in 1962, and she attended the University of Kansas before transferring to Arizona State University.