According to Daily Mail (UK), the Argentina FA official Twitter page confirmed that he ruptured his cruciate knee ligament during Friday's session.
Manuel Lanzini became the latest addition to the casualty list this week, as he tore his anterior cruciate ligament in training.
Meanwhile, Lionel Messi has said Argentina are well prepared for the World Cup and highlighted their individual quality as key.
The West Ham United player has suffered a awful ACL injury and is out of the team. All eyes will now be on Argentina coach Jorge Sampaoli to see who will be replacing Lanzini in the squad.
They will now have to deal with a new player being drafted in after Lanzini's serious injury. Or alternatively, Boca Juniors' Cristian Pavón could find himself filling in for Lanzini in Argentina's opening group game against Iceland on Saturday 16th June.